Alcohols and polyols
- (1)
- (55)
- (350)
- (41)
- (4)
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- (55)
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- (1)
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- (155)
- (1)
- (63)
- (29)
- (14)
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- (1)
- (1)
- (10)
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- (1)
- (1)
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- (1)
- (1)
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- (30)
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- (20)
- (10)
- (2)
- (10)
- (4)
- (5)
- (399)
- (6)
- (102)
- (22)
- (50)
- (31)
- (62)
- (13)
- (14)
- (1)
- (2)
- (1)
- (25)
- (6)
- (4)
- (1)
- (6)
- (1)
- (463)
- (9)
- (46)
- (10)
- (46)
- (6)
- (1)
- (6)
- (13)
- (148)
- (114)
- (9)
- (5)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (4)
- (7)
- (14)
- (2)
- (1)
- (6)
- (5)
- (1)
- (1)
- (12)
- (21)
- (5)
- (2)
- (2)
- (1)
- (2)
- (16)
- (2)
- (30)
- (1)
- (4)
- (1)
- (2)
- (1)
- (20)
- (10)
- (4)
- (15)
- (1)
- (4)
- (6)
- (2)
- (1)
- (2)
- (2)
- (2)
- (1)
- (4)
- (3)
- (1)
- (28)
- (29)
- (7)
- (3)
- (5)
- (1)
- (36)
- (5)
- (4)
- (2)
- (5)
- (4)
- (17)
- (14)
- (4)
- (5)
- (1)
- (2)
- (5)
- (1)
- (4)
- (37)
- (4)
- (2)
- (6)
- (8)
- (2)
- (2)
- (9)
- (7)
- (7)
- (2)
- (1)
- (1)
- (26)
- (1)
- (1)
- (1)
- (2)
- (1)
- (3)
- (4)
- (2)
- (1)
- (14)
- (12)
- (1)
- (3)
- (2)
- (7)
- (12)
- (1)
- (1)
- (14)
- (24)
- (1)
- (8)
- (4)
- (1)
- (2)
- (1)
- (22)
- (2)
- (6)
- (5)
- (2)
- (1)
- (5)
- (3)
- (4)
- (24)
- (5)
- (3)
- (5)
- (14)
- (1)
- (1)
- (1)
- (11)
- (3)
- (2)
- (4)
- (11)
- (2)
- (6)
- (4)
- (1)
- (3)
- (6)
- (11)
- (5)
- (4)
- (1)
- (2)
- (11)
- (14)
- (7)
- (2)
- (3)
- (1)
- (3)
- (1)
- (2)
- (1)
- (10)
- (1)
- (2)
- (4)
- (4)
- (1)
- (3)
- (1)
- (3)
- (5)
- (1)
- (1)
- (2)
- (1)
- (1)
- (10)
- (2)
- (2)
- (3)
- (7)
- (1)
- (1)
- (5)
- (4)
- (1)
- (2)
- (9)
- (4)
- (2)
- (12)
- (4)
- (1)
- (5)
- (4)
- (10)
- (2)
- (5)
- (1)
- (1)
- (1)
- (10)
- (6)
- (1)
- (2)
- (2)
- (6)
- (14)
- (2)
- (4)
- (1)
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- (1)
- (1)
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- (1)
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- (3)
- (2)
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- (3)
- (1)
- (4)
- (5)
- (1)
- (4)
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- (9)
- (1)
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- (5)
- (2)
- (1)
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- (1)
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- (1)
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- (1)
- (10)
- (1)
- (1)
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- (11)
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- (20)
- (21)
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- (1)
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- (1)
- (1)
- (7)
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- (1)
- (2)
- (1)
- (1)
- (5)
- (4)
- (3)
- (1)
- (1)
- (4)
- (6)
- (1)
- (1)
- (1)
- (5)
- (1)
- (1)
- (4)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
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- (1)
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- (1)
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- (1)
- (2)
- (2)
- (5)
- (2)
- (1)
- (1)
- (1)
- (1)
- (3)
- (14)
- (1)
- (1)
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- (1)
- (2)
- (2)
- (4)
- (1)
- (1)
- (4)
- (5)
- (2)
- (2)
- (1)
- (10)
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- (1)
- (9)
- (1)
- (8)
- (1)
- (1)
- (2)
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- (2)
- (2)
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- (1)
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- (1)
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- (5)
- (3)
- (4)
- (1)
- (1)
- (3)
- (2)
- (4)
- (1)
- (1)
- (1)
- (1)
- (4)
- (1)
- (5)
- (1)
- (7)
- (1)
- (2)
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- (7)
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- (1)
- (6)
- (1)
- (1)
- (15)
- (2)
- (1)
- (2)
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- (2)
- (1)
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- (1)
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- (12)
- (4)
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- (9)
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- (3)
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- (7)
- (1)
- (18)
- (16)
- (1)
- (4)
- (2)
- (4)
- (60)
- (5)
- (2)
- (1)
- (1)
- (30)
- (2)
- (2)
- (11)
- (81)
- (12)
- (4)
- (1)
- (3)
- (7)
- (5)
- (1)
- (81)
- (3)
- (378)
- (4)
- (40)
- (21)
- (1)
- (19)
- (1)
- (22)
- (16)
- (1)
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- (21)
- (2)
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- (1)
- (67)
- (1)
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- (7)
- (2)
- (2)
- (2)
- (7)
- (4)
- (86)
- (1)
- (5)
- (72)
- (3)
- (5)
- (238)
- (4)
- (2)
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- (21)
- (281)
- (17)
- (1)
- (6)
- (279)
- (28)
- (2)
- (25)
- (2)
- (3)
- (2)
- (2)
- (2)
- (6)
- (3)
- (2)
- (3)
- (48)
- (3)
- (418)
- (6)
- (3)
- (6)
- (5)
- (47)
- (6)
- (3)
- (1)
- (4)
- (21)
- (16)
- (2)
- (4)
- (11)
- (1)
- (8)
- (2)
- (731)
- (11)
- (3)
- (4)
- (2)
- (9)
- (1)
- (2)
- (2)
- (66)
- (2)
- (2)
- (18)
- (3)
- (4)
- (33)
- (2)
- (31)
- (39)
- (2)
- (3)
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- (3)
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Filtered Search Results
Medchemexpress LLC CCG258208 hydrochloride | 98.1% | 488.94 | 25 MG
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CCG258208 (GRK2-IN-1) hydrochloride is a potent and selective inhibitor of GRK2 (G protein-coupled receptor kinase 2) with an IC50 of 30 nM. It demonstrates significant selectivity, being 230-fold more selective over GRK5 (IC50=7.09 μM) and over 2500-fold more selective over GRK1 (IC50=87.3 μM), PKA, and ROCK1. This compound is utilized in heart failure research.
- Potent and selective GRK2 inhibitor (IC50=30 nM).
- High selectivity over GRK5 (230-fold).
- Even higher selectivity over GRK1, PKA, and ROCK1 (more than 2500-fold).
- Applicable in heart failure research.
- Shows significant improvement in βAR-stimulated contractility in mouse cardiomyocytes at concentrations as low as 0.1 μM.
- Exhibits a superior half-life *in vivo*.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC P-F-HHSiD (hydrochloride) | 175615-76-6 | 99% | 386.02 | 1 MG
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p-F-HHSiD (hydrochloride) is a selective M3 mAChR antagonist. It blocks Acetylcholine-mediated vasodilatation in human umbilical vein endothelial cells (HUVECs). This product is intended for laboratory use.
- Selective M3 mAChR antagonist
- Blocks Acetylcholine-mediated vasodilatation
- Suitable for laboratory research
- Solid appearance
- Stable under recommended storage conditions
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Prx-07034 hydrochloride | 903580-39-2 | 99.0% | C21H29Cl2N3O4S | 25 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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PRX-07034 hydrochloride is a highly selective and potent 5-HT6 receptor antagonist with a Ki of 4-8 nM and IC50 of 19 nM. Intended for research on enhancing working memory and cognitive flexibility, it shows significant 5-HT6 receptor selectivity (>100-fold over 68 other GPCRs, ion channels, and transporters). It also inhibits 5-HT1A, 5-HT1B, 5-HT1D, Dopamine D3, Histamine H2, and Opioid μ receptors. In vivo studies in rats demonstrated enhanced delayed spontaneous alternation and improved cognitive strategy switching.
- Highly selective and potent 5-HT6 receptor antagonist
- Ki of 4-8 nM and IC50 of 19 nM for 5-HT6 receptor
- Enhances working memory and cognitive flexibility
- >100-fold selectivity over 68 other GPCRs, ion channels, and transporters
- Inhibits 5-HT1A, 5-HT1B, 5-HT1D, Dopamine D3, Histamine H2, and Opioid μ receptors
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Medchemexpress LLC Fadrozole hydrochloride (CGS 16949A) | 102676-31-3 | 99.9% | C14H14ClN3 | 50 MG
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Fadrozole hydrochloride (CGS 16949A) is a potent, selective, and nonsteroidal inhibitor of aromatase with an IC50 of 6.4 nM. It inhibits estrogen production in hamster ovarian slices with an IC50 of 0.03 μM and progesterone production with an IC50 of 120 μM. Higher doses can suppress the synthesis of other cytochrome P-450 dependent steroids to varying degrees.
- Potent and selective aromatase inhibitor.
- Prevents development of benign and malignant spontaneous mammary neoplasms.
- Slows development of pituitary pars distalis adenomas and reduces incidence of spontaneous hepatocellular tumors.
- Reduces parasite burden in male and female mice by 70%.
- Augments Interleukin-6 (IL-6) serum levels and production by splenocytes.
- Nonsteroidal option for aromatase inhibition.
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Medchemexpress LLC Elacridar hydrochloride | 143851-98-3 | 99.9% | C34H34ClN3O5 | 100 MG
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Elacridar hydrochloride (GF120918A) is an orally active inhibitor of P-glycoprotein and breast cancer resistance protein (BCRP). It is used to investigate the influence of efflux transporters on agent distribution to the brain and for cancer research.
- Inhibits P-glycoprotein and BCRP
- Used in cancer research
- Investigates efflux transporter influence on brain distribution
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Medchemexpress LLC Gefitinib hydrochloride | 184475-55-6 | MFCD00952718 | 99.8% | C22H25Cl2FN4O3 | 1 G
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Gefitinib hydrochloride is a potent, selective, and orally active EGFR tyrosine kinase inhibitor, intended for research use only. It selectively inhibits EGF-stimulated tumor cell growth and blocks EGFR autophosphorylation in tumor cells. It also induces autophagy and exhibits antitumour activity.
- Potent and selective EGFR tyrosine kinase inhibitor.
- IC50 of 33 nM against EGFR.
- Selectively inhibits EGF-stimulated tumor cell growth with an IC50 of 54 nM.
- Blocks EGF-stimulated EGFR autophosphorylation in tumor cells.
- Induces autophagy.
- Exhibits antitumour activity.
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Medchemexpress LLC TENAPANOR HYDROCHLO 25 mg
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TENAPANOR HYDROCHLO 25MG
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Medchemexpress LLC AP-III-A4 HYDROCHLO 50 mg
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AP-III-A4 HYDROCHLO 50MG
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Medchemexpress LLC TENAPANOR HYDROCHLO 5 mg
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TENAPANOR HYDROCHLO 5MG
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Medchemexpress LLC TIARAMIDE HYDROCHLO 1 mg
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TIARAMIDE HYDROCHLO 1MG
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Medchemexpress LLC SB-505124 HYDROCHLO 10MM 1ML
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SB-505124 HYDROCHLO 10MM 1ML
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Medchemexpress LLC BELOTECAN HYDROCHLO 25 mg
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BELOTECAN HYDROCHLO 25MG
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Medchemexpress LLC SB-505124 HYDROCHLO 50 mg
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SB-505124 HYDROCHLO 50MG
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Medchemexpress LLC HORDENINE HYDROCHLO 5G
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HORDENINE HYDROCHLO 5G
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Medchemexpress LLC YOHIMBINE HYDROCHLO 5G
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YOHIMBINE HYDROCHLO 5G
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